Susan Hockfield Curriculum Vitae
B.A., Biology, University of Rochester, 1973
Ph.D., Anatomy (and Neuroscience), Georgetown University School of Medicine, 1979
TEACHING, RESEARCH, AND ADMINISTRATIVE POSITIONS
2012-2013 Marie Curie Visiting Professor, Harvard University, John F. Kennedy School of Government
2012-pres. President Emerita, Massachusetts Institute of Technology
2004-pres. Professor of Neuroscience, Massachusetts Institute of Technology
2004-2012 President, Massachusetts Institute of Technology
2003-2004 Provost, Yale University
2001-2004 William Edward Gilbert Professor of Neurobiology, Yale University
1998-2002 Dean, Yale University Graduate School of Arts and Sciences
1994-2004 Professor, Yale University School of Medicine, Department of Neurobiology
1991-1994 Associate Professor (tenure), Yale University School of Medicine, Section of Neurobiology
1989-1991 Associate Professor (term), Yale University School of Medicine, Section of Neurobiology
1986-1994 Director of Graduate Studies, Yale University School of Medicine, Section of Neurobiology
1985-1989 Assistant Professor, Yale University School of Medicine, Section of Neurobiology
1982-1985 Senior Staff Investigator, Cold Spring Harbor Laboratory
1980-1982 Junior Staff Investigator, Cold Spring Harbor Laboratory
1979-1980 National Institutes of Health (NIH) postdoctoral fellow, University of California, San Francisco,
Department of Anatomy and Neuroscience Program
American Academy of Arts and Sciences, Board of Directors, member, 10/2013-present
Belfer Center for Science and International Affairs, Board of Directors, member, 6/2013-present
Boston Symphony Orchestra, Board of Overseers, member, 9/2006–present
Carnegie Corporation of New York, Board of Trustees, member, 9/2006–present
General Electric Company, Board of Directors, member, 12/2006–present
Massachusetts Institute of Technology, Corporation, life member, 7/2012-present
Qualcomm Incorporated, Board of Directors, member, 7/2012-present
World Economic Forum, Foundation Board, member, 1/2008–9/2012
American Association for the Advancement of Science, member
Society for Neuroscience, member
AWARDS AND RECOGNITION
Doctor of Science (honoris causa) degree, University of Massachusetts Medical School, 2013
Doctor of Science (honoris causa) degree, University of Rochester, 2013
Pinnacle Award for Lifetime Achievement, Greater Boston Chamber of Commerce, 2013
American Academy of Rome, Carnegie Corporation/Vartan Gregorian Affiliated Fellow, 2012
Association of Alumni and Alumnæ of the Massachusetts Institute of Technology, Honorary Member, 2010
Edison Achievement Award, 2010
Royal Irish Academy, Honorary Member, 2010
Doctor honoris causa degree, University Pierre and Marie Curie, Paris, France, 2010
Doctor honoris causa degree, jointly awarded by the New University of Lisbon, the Technical University of Lisbon,
and the University of Porto, Portugal, 2009
America’s Best Leaders 2009 honoree, U.S. News & World Report and the Center for Public Leadership, John F.
Kennedy School of Government, Harvard University, 2009
Citation Award, Midwest Research Institute, 2009
Doctor of Science (honoris causa) degree, University of Edinburgh, Scotland, 2009
Doctor of Science (honoris causa) degree, Mount Sinai School of Medicine, New York University, 2009
Council on Foreign Relations, Life Member, 2007
Doctor of Science (honoris causa) degree, Brown University, 2006
Doctor of Science (honoris causa) degree, Cold Spring Harbor Laboratory, Watson School of
Biological Sciences, 2006
Honorary doctorate degree, Tsinghua University, China, 2006
Amelia Earhart Award, Women’s Union, 2005
Golden Plate Award, Academy of Achievement, 2005
American Association for the Advancement of Science, Fellow (neuroscience), 2005
Sheffield Medal, Yale University, 2004
Meliora Citation for Career Achievement, University of Rochester, 2003
Wilbur Lucius Cross Medal, Yale University Graduate School, 2003
M.A. (hon.), Yale University, 1994
Charles Judson Herrick Award, American Association of Anatomists, 1987
Grass Traveling Scientist, Society for Neuroscience, 1987
Esther A. and Joseph Klingenstein Fellowship in the Neurosciences, 1985
PHS Postdoctoral Research Award, National Institutes of Health, 1980
PROFESSIONAL AND NATIONAL SERVICE ACTIVITIES
|11/2012-present||U.S. Science Envoy, U.S. Department of State|
|2/2012–present||Sorbonne University Strategy Committee, member|
|6/2011–10/2012||Advanced Manufacturing Partnership Steering Committee, Co-Chair, sponsored by the|
|Executive Office of the President of the United States|
|12/2010-7/2012||WGBH Educational Foundation, Inc., Board of Trustees, ex officio, Institutional Trustee|
|7/2009–7/2012||Eli and Edythe L. Broad Institute of MIT and Harvard, Board of Directors, ex officio, member|
|5/2009–3/2012||Zayed Future Energy Prize, member of the Jury|
|2/2009–7/2012||Ragon Institute of MGH, MIT, and Harvard, Governance Board, ex officio, member|
|1/2009–1/2012||The Climate Group, Leadership Council, member|
|7/2008–11/2008||Association of American Universities (AAU), Task Force on the 2008 Election, member|
|8/2007–7/2012||Association of American Universities (AAU), Advisory Task Force on Indirect Costs, member|
|7/2007–3/2012||Broad Prize for Urban Education, Selection Jury, member|
|7/2007–3/2009||Carnegie Corporation of New York – Institute for Advanced Study (IAS), Commission on|
|Mathematics and Science Education, member|
|5/2007–7/2012||Council on Foreign Relations, Higher Education Working Group on Global Issues, member|
|5/2007–5/2009||Council on Competitiveness, Energy Security, Innovation and Sustainability Initiative|
|Steering Committee, member|
|5/2007–8/2009||National Math and Science Initiative, Inc., Board of Directors, member|
|2/2007–present||Massachusetts General Hospital, Scientific Advisory Committee, member|
|1/2007–7/2012||Massachusetts Life Sciences Collaborative Leadership Council, Co-Chair|
|2006–7/2012||European Humanities University, International Support Committee, member|
|7/2006–11/2006||Republic of Singapore, Research, Innovation, and Enterprise Council, member|
|5/2006–7/2012||Woods Hole Oceanographic Institution, ex officio, Corporation member|
|2/2006–2/2007||Universities Research Association, Council of Presidents, Chair|
|2005–2008||United States Department of Justice, National Security Higher Education Advisory Board,|
|2005–2007||Cogito.org, Board of Advisors, member|
|2005–2006||Association of American Universities (AAU), Task Force on Interdisciplinarity, member|
|3/2005–7/2012||Council on Competitiveness, Executive Committee, member|
|2/2005–2/2006||Universities Research Association, Council of Presidents, Vice-Chair|
|1/2005–7/2012||Lord Foundation of Massachusetts, Class B Director|
|5/2006-7/2012||Woods Hole Oceanographic Institution, Corporation member|
|2004-2007||Association of American Universities (AAU), Task Force on Export Controls, member|
|2002-2004||National Institutes of Health, National Advisory Neurological Disorders and Stroke Council,|
|2002||Council of Graduate Schools, Member of the Board|
|2002||Association of Graduate Schools, Executive Committee, member|
|2000-2004||American Association for the Advancement of Science (AAAS), Section of Neuroscience,|
|1999-2002||Human Frontier Science Program, Council of Scientists, member|
|1998–2004||Cold Spring Harbor Laboratory, Board of Trustees, member|
|1997-2002||James S. McDonnell Foundation, Brain Cancer Advisory Panel, member|
|1997||Gordon Conference on Neural Plasticity, Chair|
|1997-1999||Astra Pharmaceuticals, Neuroscience Advisory Board, member|
|1996-2002||Calvin Hill Day Care Center and Kitty Lustman Findling Kindergarten, Board Member|
|1996-2000||Hereditary Disease Foundation, Scientific Advisory Board, member|
|1995||Gordon Conference on Neural Plasticity, Co-chair|
|1994||NeuroImage, Editorial Board, member|
|1993||Learning and Memory, Editorial Board, member|
|1992-1996||Neuroscience Protocols, Editorial Board, member|
|1992-1996||Society for Neuroscience, Councilor|
|1991-1995||Hereditary Disease Foundation, Scientific Advisory Board, member|
|1990-1995||Cerebral Cortex, Editorial Board, member|
|1989-1991||Society for Neuroscience, Short Course on Basics of Molecular Biology for Neurobiologists,|
|1988-1994||Journal of Neuroscience, Editorial Board, member|
|1988-1992||National Institutes of Health, Study Section, Visual Sciences B, member|
|1988-2002||Haskins Laboratory, Board of Directors, member|
|1988-2002||Yale-New Haven Teachers Institute, University Advisory Council, member|
|1985-1997||Cold Spring Harbor Laboratory, Summer Neurobiology Program, Program Director|
|1985||Cold Spring Harbor Laboratory, Course on Molecular Cloning of Eukaryotic Genes, participant|
|1984-1986||Cold Spring Harbor Laboratory, Course on Immunoglobulins: Molecular Probes of the Nervous|
|1983||Society for Neuroscience, Short Course on Molecular Approaches to the Nervous System,|
|1981||Society for Neuroscience, Short Course on New Approaches in Developmental Neurobiology,|
|1981||Cold Spring Harbor Laboratory, Course on Neurobiology of the Leech, participant|
|1979-1980||Cold Spring Harbor Laboratory, Pain Workshop, participant|
"Manufacturing a Recovery," New York Times, August 29, 2011.
"Riding the Innovation Wave," Boston Globe, March 14, 2011, coauthored with Drew Faust.
"For Future Prosperity, Sow Seeds Now," Boston Globe, August 14, 2010, coauthored with Paul E. Jacobs.
"Immigrant Scientists Create Jobs and Win Nobels," Wall Street Journal, October 20, 2009.
"The Next Innovation Revolution," Science, February 27, 2009
"The Next Step in Stimulus: Long-Term Economic Growth," Boston Globe, February 13, 2009.
"Reimagining Energy," Washington Post, September 11, 2008.
"Gaining Ground on Cancer," Boston Globe, April 28, 2008.
"Numbers That Can Change the World," Boston Globe, April 14, 2008.
"MIT's Burgeoning Role in the Green Movement," Boston Globe, April 7, 2008.
"Investing in the Nation’s Future," Boston Globe, March 31, 2008.
"A Model for Tackling the Energy Challenge," Boston Globe, December 13, 2006.
"The Innovation Equation," Boston Globe, October 12, 2006.
"Women in Math, Engineering, and Science: Drawing on Our Country's Entire Talent Pool," Boston Globe, February 12, 2005, coauthored with John Hennessy and Shirley Tilghman.
- Hockfield, S. and S. Gobel. Neurons in and near nucleus caudalis with long ascending projection axons demonstrated by retrograde labeling with horseradish peroxidase. Brain Research 139: 333-339 (1978).
- Hockfield, S. and S. Gobel. An anatomical demonstration of projections to the medullary dorsal horn (Trigeminal Nucleus Caudalis) from rostral trigeminal nuclei and the contralateral caudal medulla. Brain Research 252: 203-211 (1982).
- McKay, R. and S. Hockfield. Monoclonal antibodies distinguish antigenically discrete neuronal types in thevertebrate central nervous system. Proc. Natl. Acad. Sci. U.S.A. 79: 6747-6751 (1982).
- Hockfield, S. and R. McKay. Monoclonal antibodies demonstrate the organization of axons in the leech. J. Neurosci. 3: 369-375 (1983).
- Hockfield, S. and R. McKay. A surface antigen expressed by a subset of neurons in the vertebrate central nervous system. Proc. Natl. Acad. Sci. U.S.A. 80: 5758-5761 (1983).
- Hockfield, S., R. McKay, S. Hendry, and E. G. Jones. A surface antigen that identifies ocular dominance columns in cortical area 17 and laminar features of the lateral geniculate nucleus. Cold Spring Harbor Symp. Quant. Biol. 48: 877-889 (1983).
- McKay, R., S. Hockfield, and J. Johansen. The organization of molecularly distinct axons in the leech connective. Cold Spring Harbor Symp. Quant. Biol. 48: 599-610 (1983).
- McKay, R., S. Hockfield, J. Johansen, I. Thompson, and K. Frederiksen. Surface molecules identify groups of growing axons. Science 222: 788-794 (1983).
- Hendry, S., S. Hockfield, E. G. Jones, and R. McKay. A monoclonal antibody that identifies subsets of neurons in the central visual system of the monkey and cat. Nature 307: 267-269 (1984).
- Johansen, J., S. Hockfield, and R. McKay. Distribution and morphology of nociceptive cells in the central nervous system of the leech. J. Comp. Neurol. 226: 255-262 (1984).
- Johansen, J., S. Hockfield, and R. McKay. Axonal projections of mechanosensory neurons in the connective and peripheral nerves of the leech. J. Comp. Neurol. 226: 263-273 (1984).
- McKay, R., J. Johansen, and S. Hockfield. Monoclonal antibody identifies a 63,000 dalton antigen found in all central neuronal cell bodies but in only a subset of axons in the leech. J. Comp. Neurol. 226: 448-455 (1984)
- Hockfield, S. and R. McKay. Identification of major cell classes in the developing mammalian nervous system. J. Neurosci. 5: 3310-3329 (1985).
- Hockfield, S. A novel cerebellar neuron identified by a monoclonal antibody generated with immunosuppressive and rapid immunization strategies. Science 237: 67-70 (1987).
- Sur, M., D. Frost, and S. Hockfield. Expression of a cell surface antigen on Y-cells in the cat lateral geniculate nucleus is regulated by visual experience. J. Neurosci. 8: 874-882 (1988).
- Hishinuma, A., S. Hockfield, R. McKay, and J. Hildebrand. Monoclonal antibodies reveal cell type-specific antigens in the sexually dimorphic olfactory system of Manduca sexta. 1. Generation of monoclonal antibodiesand partial characterization of the antigens. J. Neurosci. 8: 296-307 (1988).
- Hishinuma, A., S. Hockfield, R. McKay, and J. Hildebrand. Monoclonal antibodies reveal cell type-specific antigens in the sexually dimorphic olfactory system of Manduca sexta. 2. Expression of antigens during postembryonic development. J. Neurosci. 8: 308-315 (1988).
- Hendry, S., E. G. Jones, S. Hockfield, and R. McKay. Neuronal populations stained with the monoclonal antibody, Cat-301, in the mammalian cerebral cortex and thalamus. J. Neurosci. 8: 518-542 (1988).
- Kalb, R. and S. Hockfield. Molecular evidence for early activity-dependent development of hamster motor neurons. J. Neurosci. 8: 2350-2360 (1988).
- Zaremba, S., A. Guimaraes, R. G. Kalb, and S. Hockfield. Characterization of an activity-dependent, neuronal surface proteoglycan identified with monoclonal antibody Cat-301. Neuron 2: 1207-1219 (1989).
- Friedman, B., J. A. Black, S. Hockfield, S. G. Waxman, and B. R. Ransom. Antigenic abnormalities in fiber tract astrocytes of myelin-deficient rats: an immunocytochemical study in the olfactory cortex. Dev. Neurosci. 11, 99-111 (1989).
- McGuire, P. K., S. Hockfield, and P. Goldman-Rakic. The distribution of Cat-301 immunoreactivity in the frontal and parietal lobes of the macaque monkey. J. Comp. Neurol. 288, 280-296 (1989).
- Geschwind, D. H. and S. Hockfield. Identification of proteins that are developmentally regulated during early cerebral corticogenesis in the rat. J. Neurosci. 9: 4303-4317 (1989).
- Friedman, B., J. Black, K. Woodruff, S. Hockfield, and S. Waxman. Monoclonal antibody RIP produces Golgilike staining of mature oligodendrocytes in situ. Glia 2: 380-390 (1989).
- Mize, R. R. and S. Hockfield. Cat-301 antibody selectively labels neurons in the Y-innervated laminae of the cat superior colliculus. Visual Neurosci. 3: 433-443 (1989).
- Kalb, R. and S. Hockfield. Large diameter primary afferent input is required for developmental expression of a proteoglycan on the surface of motor neurons. Neuroscience 34: 391-401 (1990).
- Hockfield, S., R. Tootell, and S. Zaremba. Molecular differences among neurons reveal an organization of human visual cortex. Proc. Natl. Acad. Sci. 87:3027-3031 (1990).
- Friedman, B., S. Zaremba, and S. Hockfield. Monoclonal antibody Rat-401 recognizes Schwann cells in mature and developing peripheral nerve. J. Comp. Neurol. 295: 43-51 (1990).
- DeYoe, E. A., S. Hockfield, H. Garren, and D. Van Essen. Antibody labeling of functional subdivisions in visual cortex: Cat-301 in V1, V2, V3 and MT of the Macaque monkey. Visual Neurosci. 5: 67-81 (1990).
- Sahin, M. and S. Hockfield. Molecular identification of the Lugaro cell in the cat cerebellar cortex. J. Comp. Neurol. 301: 575-584 (1990).
- Zaremba, S., J. R. Naegele, C. J. Barnstable, and S. Hockfield. Monoclonal antibodies Cat-301 and VC1.1 define different high molecular weight glycoconjugates. J. Neurosci. 10: 2985-2995 (1990).
- Guimarães, A., S. Zaremba, and S. Hockfield. Molecular and morphological changes in cat lateral geniculate nucleus and visual cortex induced by visual deprivation are revealed by monoclonal antibodies Cat-301 and Cat-304. J. Neurosci. 10: 3014-3024 (1990).
- Hockfield, S. and M. Sur. Monoclonal antibody Cat-301 identifies Y-cells in the dorsal lateral geniculate nucleus of the cat. J. Comp. Neurology 300: 320-330 (1990).
- Kalb, R. G. and S. Hockfield. Induction of a neuronal proteoglycan by the NMDA receptor in the developing spinal cord. Science 250: 294-296 (1990).
- Hockfield, S., S. Zaremba, R. G. Kalb, and H. Fryer. Expression of neural proteoglycans correlates with the acquisition of mature neuronal properties in the mammalian brain. Cold Spring Harbor Sympo. Quant. Biol. 55 505-514 (1990).
- Marshall, J., K. A. Martin, M. Picciotto, S. Hockfield, A. C. Nairn, and L. K. Kaczmarek. Identification and localization of a dogfish homologue of human cystic fibrosis transmembrane conductance regulator. J. Biol. Chem. 266: 22749-22754 (1991).
- Fryer, H. J. L., G. M. Kelly, L. Molinaro, and S. Hockfield. The high molecular weight Cat-301 chondroitin sulfate proteoglycan from brain is related to the large aggregating proteoglycan from cartilage, aggrecan. J. Biol. Chem. 267: 9874-9883 (1992).
- Martin, K. A., S. Grant, and S. Hockfield. The mas proto-oncogene is developmentally regulated in the rat central nervous system. Dev. Brain Res. 68: 75-82 (1992).
- Perney, T., J. Marshall, K. A. Martin, S. Hockfield, and L. K. Kaczmarek. Expression of the mRNAs for the Kv3.1 potassium channel gene in the adult and developing rat brain. J. Neurophysiol. 68: 756-766 (1992).
- Kalb, R. G., M. Lidow, and S. Hockfield. NMDA receptors are transiently expressed in the developing spinal cord ventral horn. Proc. Natl. Acad. Sci. U.S.A. 89: 8502-8506 (1992).
- Kalb, R. G. and S. Hockfield. Activity-dependent development of spinal cord motor neurons. Brain Res. Reviews, 17: 283-289 (1992).
- Martin, K. A. and S. Hockfield. Expression of the mas proto-oncogene in the rat hippocampal formation is regulated by neuronal activity. Mol. Brain Res. 19: 303-309 (1993).
- Sahin, M. and S. Hockfield. Identification of putative protein tyrosine phosphatases in developing rat brain. J. Neurosci. 13: 4968-4978 (1993).
- Kind, P., C. Blakemore, H. Fryer, and S. Hockfield. Identification of proteins down-regulated during the postnatal development of the cat visual cortex. Cerebral Cortex 4: 361-375 (1994).
- Kalb, R. G. and S. Hockfield. Electrical activity in the neuromuscular unit can influence the molecular development of motor neurons. Developmental Biology 162: 539-548 (1994).
- Jaworski, D. M., G. Kelly, and S. Hockfield. BEHAB, a new member of the proteoglycan tandem repeat family of hyaluronan binding proteins, that is restricted to the brain. J. Cell Biology 125: 495-509 (1994).
- Sahin, M., J. J. Dowling, and S. Hockfield. Seven protein tyrosine phosphatases are differentially expressed in the developing rat brain. J. Comp. Neurol. 351: 617-631 (1995).
- Minturn, J., D. Geschwind, H. J. L. Fryer, and S. Hockfield. Early postmitotic neurons transiently express TOAD-64, a neural specific, membrane associated protein. J. Comp. Neurol. 355: 369-379 (1995).
- Jaworski, D. M., G. Kelly, and S. Hockfield. The CNS specific hyaluronan-binding protein, BEHAB, is expressed in ventricular zones coincident with gliogenesis. J. Neurosci. 15: 1352-1362 (1995).
- Thormodsson, F. R., L. J. Redmond, and S. Hockfield. Identification of nuclear proteins that are developmentally regulated in embryonic rat brain. J. Neurochemistry 64: 1919-1927 (1995).
- Boyne, L. J., K. Martin, S. Hockfield, and I. Fischer. Expression and distribution of phosphorylated MAP1B in growing axons of cultured hippocampal neurons. J. Neuroscience Res. 40: 439-450 (1995).
- Sahin, M., S. A. Slaugenhaup, J. F. Gusella, and S. Hockfield. A protein tyrosine phosphatase, PTPH1, is expressed in a segment-specific pattern in the rat diencephalon. Proc. Natl. Acad. Sci. 92: 7859-7863 (1995).
- Minturn, J., H. J. L. Fryer, D. Geschwind, and S. Hockfield. TOAD-64, a gene expressed early in neuronal differentiation in the rat, is related to unc-33, a C. elegans gene involved in axon outgrowth. J. Neurosci. 15: 6757-6766 (1995).
- Redmond, L. J., S. Hockfield, and M. Morabito. The divergent homeobox gene PBX1 is expressed in the postnatal subventricular zone and the interneurons of the olfactory bulb. J. Neurosci. 16: 2972-2982 (1996).
- Jaworski, D. M., G. M. Kelly, J. M. Piepmeier, and S. Hockfield. BEHAB (Brain Enriched Hyaluronan Binding) is expressed in surgical samples of glioma and in intracranial grafts of invasive glioma cell lines. Cancer Research 56: 2293-2298 (1996).
- Geschwind, D. H., G. Kelly, H. J. L. Fryer, and S. Hockfield. Identification and characterization of novel developmentally regulated proteins in rat spinal cord. Dev. Brain Research 97: 62-70 (1996).
- Kind, P. K., G. Kelly, H. J. L. Fryer, C. Blakemore, and S. Hockfield. PLC-ß1 is present in the botrysome, an intermediate compartment-like organelle, during periods of developmental plasticity in cat visual cortex. J. Neurosci. 17: 1471-1480 (1997).
- Redmond, L. J., H. Xie, L. Ziskind-Conhaim, and S. Hockfield. Cues intrinsic to the spinal cord determine the pattern and timing of innervation by primary afferent axons. Developmental Biology 182: 205-218 (1997).
- Lander, C., P. Kind, M. Maleski, and S. Hockfield. A family of activity-dependent neuronal cell-surface chondroitin sulfate proteoglycans in cat visual cortex. J. Neurosci. 17: 1928-1939 (1997).
- Maleski, M. and S. Hockfield. Glial cells assemble hyaluronan-based pericellular matrices in vitro. Glia 20: 193-202 (1997).
- Lurie, D. I., T. R. Pasic, S. Hockfield, and E. W. Rubel. Development of Cat-301 immuno-reactivity in auditory brainstem nuclei of the gerbil. J. Comp. Neurology 380: 319-334 (1997).
- Lander, C., H. Zhang, and S. Hockfield. Neurons produce a neuronal cell-surface associated chondroitin sulfate proteoglycan. J. Neurosci. 18: 174-183 (1998).
- Zhang, H., G. Kelly, C. Zerillo, D. M. Jaworski, and S. Hockfield. Expression of a cleaved, brain specific, extracellular matrix protein mediates glioma cell invasion in vivo. J. Neurosci. 18: 2370-2376 (1998).
- Jaworski, D. M., G. Kelly, and S. Hockfield. Intracranial injury acutely induces the expression of the secreted isoform of the CNS-specific hyaluronan-binding protein BEHAB/Brevican. Experimental Neurology 157: 327-337 (1999).
- Matthews, R. T., S. C. Gary, C. Zerillo, M. Pratta, K. Solomon, E. C. Arner, and S. Hockfield. BEHAB/Brevican Cleavage in a glioma cell line is mediated by an ADAMTS family member. J. Biol. Chem. 275: 22695-703 (2000).
- Gary, S. C., C. A. Zerillo, V. L. Chiang, J. U. Gaw, G. Gray, and S. Hockfield. cDNA cloning, chromosomal localization, and expression analysis of human BEHAB/brevican, a brain specific proteoglycan regulated during cortical development and in glioma. Gene 256: 139-147 (2000).
- Nutt, C. L., C. Zerillo, G. Kelly, and S. Hockfield. BEHAB (Brain Enriched Hyaluronan Binding)/ Brevican Increases Aggressiveness of CNS-1 Gliomas in Lewis Rats. Cancer Res. 61: 7056-7059 (2001).
- Benvenuti, S., R. Cramer, C. C. Quinn, J. Bruce, M. Vzelebil, S. Corless, J. Bond, A. Yang, S. Hockfield, A. L. Burlingame, M. D. Waterfield, and P. S. Jat. Differential proteome analysis of replicative senescence in rat embryonic fibroblasts. Mol. And Cell. Proteomics 1: 280-292 (2002).
- Matthews, R. T., G. Kelly, C. Zerillo, G. Gray, M. Tiemeyer, and S. Hockfield. Aggrecan glycoforms contribute to the molecular heterogeneity of perineuronal nets. J. Neurosci. 22: 7536-7547 (2002).
- Quinn, C. Q., E. Chen, T. G. Kinjo, G. Kelly, A. W. Bell, P. S. McPherson, and S. Hockfield. TUC-4b, a novel TUC family variant, regulates neurite outgrowth and associates with vesicle in the growth cone. J. Neurosci. 23: 2815-2823 (2003).
- Viapiano, M. S., R. T. Matthews, and S. Hockfield. A novel membrane-associated glycovariant of BEHAB/brevican is upregulated during rat brain development and in a rat model of invasive glioma. J. Biol. Chem. 278: 33239-33247 (2003).
- Viapiano, M. S., W. Bi, J. Piepmeier, S. Hockfield, and R. T. Matthews. Novel tumor-specific isoforms of BEHAB/brevican identified in human malignant gliomas. Cancer Research 65: 6726-6733 (2005):
- Dino, M. R., S. Harroch, S. Hockfield, and R. T. Matthews. Monoclonal antibody Cat-315 detects a glycoform of receptor protein tyrosine phosphatase beta/phosphacan early in CNS development that localizes to extrasynaptic sites prior to synapse formation. Neuroscience 142: 1055-69 (2006).
Reviews and Chapters
- Gobel, S., W. M. Falls, and S. Hockfield. The division of the dorsal and ventral horns of the mammalian caudal medulla into eight layers using anatomical criteria. In: Pain the Trigeminal Region, Anderson and Matthews (eds.). Elsevier-North Holland, Amsterdam-New York, 443-453 (1977).
- Gobel, S. and S. Hockfield. An anatomical analysis of the synaptic circuitry of layers I, II, and II of trigeminal nucleus caudalis in the cat. In: Pain in the Trigeminal Region. Anderson and Matthews (eds.). Elsevier-North Holland, Amsterdam-New York, 203-211 (1977).
- Gobel, S., S. Hockfield, and M. A. Ruda. Anatomical similarities between medullary and spinal dorsal neurons. In: Oral-Facial Sensory Motor Functions. Y. Kawamura and R. Dubner (eds.). Quintessence, Tokyo, 211-223 (1981).
- Hockfield, S., B. Zipser, and R. McKay. Light and electron microscope localization of monoclonal antibodies to leech neural tissue. In: New Approaches in Development Neurobiology. Society for Neuroscience, 25-33 (1981).
- Zipser, B., S. Hockfield, and R. McKay. Immunological identification of specific neurons. In: Neurobiology of the Leech. K. J. Muller, J. G. Nicholls and G. S. Stent (eds.). Cold Spring Harbor Lab. Publications, Cold Spring Harbor, N.Y., 235-247 (1981).
- Hockfield, S. Molecular correlates of structural and organizational features of mammalian CNS demonstrated with monoclonal antibodies. In: Molecular Approaches to the Nervous System. Society for Neuroscience, 54-62 (1983).
- Hockfield, S., K. Frederiksen, and R. McKay. The differentiation of cell types in the vertebrate CNS. In: Molecular Aspects of Neurobiology, R. Levi-Montalcini and E. Kandel (eds.), Springer-Verlag, New York and Berlin (1986).
- Hockfield, S., R. Kalb, and A. Guimaraes. Experience-dependent expression of neuronal cell surface molecules. In: Neuroimmune Networks: Physiology and Diseases. E. Goetzl, Alan R. Liss (eds.). New York, 57-63 (1989).
- Hockfield, S. Neuronal carbohydrates. Science 247: 733 (1990).
- Hockfield, S. Proteoglycans in neural development. Seminars in Developmental Biology, Saunders. Volume 1, 55-63 (1990).
- Hockfield, S. Molecular correlates of activity-dependent development and synaptic plasticity. In: Synaptic Plasticity, M. Baudry, et al. (eds.), MIT Press, Boston (1993).
- Hockfield, S. and R. Kalb. Activity-dependent structural changes during neuronal development. Current Opinions in Neurobiology 3: 87-92 (1993).
- Hockfield, S. Visual cortical dysfunction. Neurology 43: 453-454 (1993).
- Carlson, S. S. and S. Hockfield. Proteoglycans in the CNS extracellular matrix. In: Extracellular Matrix. W. D. Comper (ed.). Harwood, Victoria, Australia (1995).
- Sahin, M. and S. Hockfield. Receptor tyrosine phosphatases in CNS development. In: Receptor Dynamics in Neural Development. C. Shaw (ed.). CRC Press, 119-138 (1996).
- Fryer, H. J. L. and S. Hockfield. The role of polysialic acid and other carbohydrate polymers in neural structural plasticity. Current Opinions in Neurobiology 6: 113-118 (1996).
- Jaworski, D. M., G. Kelly, and S. Hockfield. The CNS-specific hyaluronan binding protein, BEHAB, is expressed during periods of glial cell generation and motility. Seminars in the Neurosciences 8: 391-396 (1996).
- Lander, C. and S. Hockfield. The extracellular matrix of the peripheral and central nervous systems. In: Encyclopedia of Neuroscience. G. Adelman and B. Smith (eds.). Elsevier, 697-702 (1999).
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U.S. Patent 5,635,370. Filed 4/8/94; issued 6/3/97. “DNA encoding BEHAB, a brain hyaluronan-binding protein,
and recombinant expression systems for production of BEHAB polypeptides.”
U.S. Patent 6,884,619. Filed 7/16/02; issued 4/26/05. “Inhibition of BEHAB cleavage and primary central
nervous system (CNS) tumors.”
U.S. Patent application 20030068661. Filed 4/10/03. “Inhibition of BEHAB cleavage and primary central
nervous system (CNS) tumors.”
U.S. Patent application 20030224976. Filed 12/4/03. “Compositions, methods and kits relating to BEHAB and
primary CNS tumors.”
U.S. Patent application 20060166290. Filed 7/27/06. “Primary central nervous system tumor specific BEAB isoforms.”
U.S. Patent application 20090117595. Filed 5/7/09. “Primary central nervous system tumor specific BEHAB isoforms.”